Igama lomkhiqizo: IGuanidine Hydrochloride

Aminoformamidine hydrochloride noma iGuanidinium chloride

Ukubukeka: isigaxa esimhlophe noma esiphuzi.

Idatha yendawo yokuhlala

1. Uhlamvu: isigaxa esimhlophe noma esiphuzi

2. Iphuzu lokuncibilika (℃): 181-183

3.Ukuqina kwesihlobo (g / ml, 20/4 ℃): 1.354

4.Umswakamo: 228g emanzini angu-100g, ama-76g ku-100g methanol nama-24g ku-100g ethanol ngo-20 ℃. Cishe akunakuncibilika ku-acetone, i-benzene ne-ether.

5. Inani le-PH (4% isixazululo samanzi, 25 ℃): 6.4

Izakhiwo nokuqina

Lo mkhiqizo awuzinzile futhi ungafakwa i-hydrolyzed ibe yi-ammonia ne-urea esixazululweni samanzi, ngakho-ke ubuthi bayo bufana nobuka-urea. IGuanidine kanye nokutholakala kwayo ngokuvamile kunobuthi kakhulu kune-urea.

Inhloso: 1. Ingasetshenziswa njengomuthi ophakathi nendawo wemithi, isibulala-zinambuzane, udayi nokunye ukuhlanganiswa kwezinto eziphilayo. Ingasetshenziselwa ukuhlanganisa i-2-Aminopyrimidine, 2-amino-6-methylpyrimidine ne-2-amino-4,6-dimethylpyrimidine. Kuyinto ephakathi yokwenza i-sulfadiazine, i-sulfamethylpyrimidine ne-sulfadimidine.

2. IGuanidine hydrochloride (noma i-guanidine nitrate) iphendula nge-ethyl cyanoacetate ukwakha i-2,4-diamino-6-hydroxypyrimidine, esetshenziselwa ukuhlanganisa i-anti anemia drug folic acid. Ingasetshenziswa futhi njenge-antistatic agent yezintambo zokwenziwa.

3. Ingasetshenziswa futhi njenge-protein denaturant.

1. Njenge-denaturant eqinile ekuhlolweni kokukhipha i-RNA ephelele. Isixazululo seGuanidine hydrochloride singahlakaza amaprotheni, sidale ukulimala kwesakhiwo samaseli, ukulimala kwesakhiwo samaprotheni enuzi, kwehlukane ne-nucleic acid, ngokungeziwe, i-RNase ingavulwa ngokunciphisa i-ejenti efana ne-guanidine hydrochloride.

indlela yokwenza

Kusetshenziswa usawoti we-dicyandiamide kanye ne-ammonium (ammonium chloride) njengezinto zokusetshenziswa, i-guanidine hydrochloride ongahluziwe yatholwa ngokuncibilika kokuphendula ngo-170-230 ℃, futhi umkhiqizo ophelile watholwa ngokucwenga.

Isilawuli soxhumana nabo

1. Musa ukuhogela uthuli

2. Kuyingozi uma kugwinywa

3. Ukucasulwa kwamehlo

4. Ukucasulwa kwesikhumba

Ukuvikelwa komuntu siqu

1. Gqoka izingubo zokuzivikela ukuze ugweme ukuthintana ngqo noma ukuhogela umoya; 2. Ungaphuzi, ungadli noma ungabhemi emsebenzini; 3. Sebenzisa izingilazi zokuphepha